Response to letter to the editors "Re: Byung-Do Lee, Wan Lee, Kyung-Hwan Kwon, Moon-Ki Choi, Eun-Joo Choi and Jung-Hoon Yoon. Glandular odontogenic cyst mimicking ameloblastoma in a 78-year-old female: a case report. Imaging Science in Dentistry 2014; 44(3): 249-52."

Thank you for your attention to our study and wonderful questions. Our reply is as below. Question) The title of the article states that the case is about a glandular odontogenic cyst (GOC) mimicking am-eloblastoma. The history (slow expansion, no symptoms) and the radiographic appearance of the lesion (lobulated, well-defined margin, erosion and perforation of the lin-gual cortex, root resorption of the adjacent teeth) may suggest ameloblastoma, but this set of diagnostic factors is not specific to this particular type of lesion. Therefore, we believe this really isn't a case of " mimicry ". Would it not have been more appropriate to define this lesion as mimicry in a case where there was another feature specific to ameloblastoma? Answer) It has been reported that GOC and ameloblas-toma show similar radiological features such as a lobulat-ed margin, perforation of the cortex, and root resorption of the adjacent teeth , although these are not specific features. Ameloblastoma is the one of most common benign tumors of the jaw, and extensive root resorption is a characteristic feature of ameloblastoma. We made a tentative diagnosis based primarily on the prevalence of this benign tumor. But histopathological findings revealed that this case was a GOC. Our title is " Glandular odontogenic cyst mimicking ameloblastoma " because ameloblastoma is the representative benign tumor of the posterior mandible. Question) Another point to mention is that the authors refer to the radiographic appearance of multiple foci and the cortical perforation as being helpful in distinguishing the GOC from ameloblastoma. But this radiographic feature also occurs in ameloblastoma, so with all due respect, we do not understand how it could be helpful in distinguishing between the two types of jaw lesions radiograph-ically. Answer) GOC and ameloblastoma may show common radiographic features of cortical perforation. The GOC has two clinically important attributes: a high recurrence rate and an aggressive growth potential. 1 Our lesion showed multiple cortical perforation in the radiolucent lesion (26.0 mm × 11.3 mm), which indicated some aggressiveness. Our view of the above distinction was based on this description from a previous study: Radiological features which may be helpful in distinguishing multilocular GOC's from ameloblastomas include irregular loculations and a partially sclerotic border with foci of perforation. 2 Question) As we read the article, we all agreed that it was not very clear when the histopathological examination was performed. It was either done on a biopsy taken …